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Search for "PET/SPECT imaging" in Full Text gives 1 result(s) in Beilstein Journal of Organic Chemistry.

Amyloid-β probes: Review of structure–activity and brain-kinetics relationships

  • Todd J. Eckroat,
  • Abdelrahman S. Mayhoub and
  • Sylvie Garneau-Tsodikova

Beilstein J. Org. Chem. 2013, 9, 1012–1044, doi:10.3762/bjoc.9.116

Graphical Abstract
  • relationships with regards to affinity for target and brain kinetics. Several probes discussed herein show particularly promising results and will be of immense value moving forward in the fight against AD. Keywords: Alzheimer’s disease; in vivo detection; near-infrared fluorescence probes; PET/SPECT imaging
  • resulted in a variety of radiolabeled molecular probes for in vivo PET/SPECT imaging. The scaffolds from which these newer radiolabeled probes are derived include chalcone (5) and its conformationally restricted analogues flavone (6) and aurone (7); stilbene (8) and its analogues diphenyl-1,2,4-oxadiazole
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Published 28 May 2013
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